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The engine of MBLresearch was strong in 2022, with abundant and significant grants awarded and papers published. Among the year's highlights were major scientific prizes received, positive media coverage, and a number of papers issuing from the ��Ůֱ������'s Advanced Research Training Courses.

Award-Winning Science

In September, the Breakthrough Prize in Life Sciences was awarded to Clifford Brangwynne and Anthony Hyman for the discovery of a new organizing principle in cells, first recognized while they were teaching in the 2008 MBLPhysiology course. Their observation of cells forming liquid-like compartments stimulated an exciting new paradigm in biology and biomedicine, with much of the field’s early groundwork laid at the MBL().

Soon after, MBLTrustee Timothy Springer received the Lasker Basic Medical Research Award, often considered a harbinger of a Nobel Prize. Springer, Richard O. Hynes and Erkki Ruoslahti were honored for original discoveries concerning the integrins, cell-adhesion proteins now related to an astonishing array of fundamental processes. Springer conducted collaborative research on the integrins in the ��Ůֱ������’s Whitman Center in the mid-2010s.

Speaking of the MBLCourses …

Living up to their reputation for creative science, the ��Ůֱ������’s Advanced Research Training Courses incubated several papers that were published in 2022. To name a few: A study in on improving resolution in fluorescence microscopy acknowledges the Analytical and Quantitative Light Microscopy course, in which co-author Alejandro Linares was a student. A protocol for live imaging of adult C. elegans sprang from the MBLEmbryology course; and Neural Systems & Behavior faculty member Michael Brecht and student Senmiao Sun illuminated torpor in the smallest known mammal, the Etruscan shrew, in . The fount of discovery in the MBLcourses flows!

In the Media Spotlight

Cephalopod research at MBLcontinues to attract media attention and public fascination. Last spring, The New York Times profiled ��Ůֱ������'s initiative to develop cephalopods as new research organisms in an extensive feature. Other big cephalopod news stories included coverage of research led by MBLGrass Fellow/UChicago graduate Z. Yan Wang; and a major study in Nature Communications comparing the genomes of one octopus and two squid species, including the local squid Doryteuthis, led by ��Ůֱ������’s Carrie Albertin.

Among the other MBLstories garnering news and social media attention last year were the discovery of a novel DNA modification system by Irina Arkhipova’s lab in the Bay Paul Center; and the first model of how the day/night cycle affects marine phytoplankton, led by Joe Vallino in the Ecosystems Center.

Finally, both and media outlets reported on the initiative to prepare the village for climate change impacts. The MBLis a partner in the private-public initiative.